Avastin® (bevacizumab), 100mg/4mL and 400mg/16 mL vials, is a Prescription Medicine used to treat metastatic (spreading) colorectal, kidney, breast, brain and lung cancers. Do not use Avastin if: you have had an allergic reaction to Avastin, any of its ingredients or other antibodies, or if you have been coughing or spitting up blood. Tell your doctor if: you are pregnant or breast-feeding, or plan to become pregnant or breast-feed, you have inflammation of the bowel or stomach ulcers, high blood pressure, a history of bleeding, blood clots, low white blood cells (neutropenia), stroke or bleeding in your lungs, have had major surgery in the last 28 days or a wound that has not healed properly, have heart disease, have/have had a fistula, have ever received anthracylines (e.g. doxorubicin) for cancer or radiotherapy to your chest, you are >65 years of age, or you are taking any other medicines. Possible unwanted effects include: Common: high blood pressure (symptoms include, blurred vision, ringing in the ears), body pain, tiredness/weakness, diarrhoea, constipation or rectal bleeding, nausea, sore mouth or mouth ulcers, loss of appetite, being thirsty, shortness of breath, wheezing, runny, blocked or bleeding nose, dry, scaling or inflamed skin, change in skin colour, rash, itching/hives on skin, taste changes, sore, inflamed or watering eyes, dizziness/faintness, headache, changes in your voice, fever, recurring or severe infections. Serious (rare): severe body or stomach pain or cramps, headache, severe diarrhoea, blood in the stools, nausea and vomiting, coughing or spitting up blood, pain and/or swelling in the lower legs, feet or hands, severe bleeding; problems with your wound healing, seizures, sleepiness/drowsiness, feelings of numbness or tingling in feet or hands, dry mouth with thirst and/or darkened urine, increased heart rate with difficulty breathing (shortness of breast). Ask your oncologist if Avastin is right for you. Use strictly as directed. If symptoms continue or if you experience side effects or would like further information, please talk to your oncologist or pharmacist, or visit www.medsafe.govt.nz for Avastin Consumer Medicine Information. Avastin is not a cure for cancer. Avastin is an unfunded medicine. You will need to pay for this medicine. A prescription charge and normal oncologist fees apply.

Consumer panel based on CMI dated 30 November 2011. Roche Products (New Zealand) Limited, Auckland. Phone: 0800 656 464. www.roche.co.nz. All trademarks mentioned herein are protected by law.

For more information please view the Avastin Consumer Medicine Information. Access to this site is subject to the terms in our Legal Statement; you accept these terms by continuing to access this site. ID1212/DA1712EG/2012APR. Last TAPS approval 05 October 2009 (NA 3768)

This website was last updated April 2012. © 2012 Roche Products (New Zealand) Ltd.